July 2016
Postdoctoral Position Available.
We are looking for people who are interested in studying the biophysics of transcription to join the lab. The ideal candidate will have experience in single-molecule biophysics techniques including optical tweezers, magnetic tweezers, and/or single-molecule fluorescence. Send CV, a description… Read More »Postdoctoral Position Available.
Eric presents at the TB Summit in London.
The lab’s work on the regulation of transcription in M. tuberculosis was presented at the TB summit in London. The talk focused on the regulation of open complex by the essential transcription factors: CarD and RbpA.
Welcome Young Science Program student Vishal Shah.
High school rising senior Vishal Shah currently attends Marquette High School in Chesterfield, Missouri. He is spending the summer in the lab working on the mechanism of start-site scanning during transcription initiation in S. cerevisiae.
New Publication in NAR: Cooperative stabilization of mycobacterial open complexes by RbpA and CarD.
Transcriptional regulation in mycobacteria tuberculosis is dependent on these two essential transcription factors. Here we show that open complex stabilization by RbpA displays a different kinetic signature than CarD. More importantly, the two interact with RNA polymerase initiation complexes cooperatively.… Read More »New Publication in NAR: Cooperative stabilization of mycobacterial open complexes by RbpA and CarD.