This research was in collaboration with the laboratories of Dylan Taatjes at UC Boulder, Steve Hahn at the Fred Hutchinson Cancer Research Center, and Susan Tsutakawa at LBNL. By comparing the double-stranded DNA processivity of the TFIIH motor subunit involved in transcription initiation, we propose a mechanistic explanation for why different Eukaryotes display distinct start-site usage patterns. Click the image below to go to the paper.