Eric and Drake traveled to Baltimore, MD to present their work at the 2019 Biophysical Society Meeting and eat crab cakes. Even better, Drake was chosen as a student travel awardee! A great meeting! Thank you BPS!
The lab’s new resource for performing calculations of regulated transcriptional flux ratios across promoter space has been published in PNAS. Click here to see the paper.
We contributed kinetic and thermodynamic measurements of the effects of mutant RbpA constructs on the equilibrium between open and closed complex. These mutants were used to dissect the genome-wide regulation of mycobacterial transcription in M. tuberculosis. Interestingly, RbpA mutants led to both up-regulation or down-regulation in a promoter specific manner suggesting the ability of RbpA […]
