The lab contributed to recent work on RbpA-based transcriptional regulation genome-wide published in the Journal of Bacteriology.
We contributed kinetic and thermodynamic measurements of the effects of mutant RbpA constructs on the equilibrium between open and closed complex. These mutants were used to dissect the genome-wide regulation of mycobacterial transcription in M. tuberculosis. Interestingly, RbpA mutants led… Read More »The lab contributed to recent work on RbpA-based transcriptional regulation genome-wide published in the Journal of Bacteriology.