Recent results using transcript flux calculations to help model RNA-seq results published in PNAS.
A new manuscript from the Stallings Lab shows how our flux calculations can provide context for understanding in vivo transcription regulation.
News
Drake Jensen’s work on promoter escape in Mtb published in Nucleic Acids Research!
Drake used stopped-flow experiments and kinetic modeling to show that both CarD and RbpA slow promoter escape in Mycobacterium tuberculosis. Interestingly, they also have effects on the rates of initial transcription. Click here to read more!
Farewell Abheek!
The lab said goodbye to undergraduate extraordinaire, Abheek Raviprasad as he heads off to the University of Florida to begin medical school next fall. All the best Abheek and keep in touch!
Ankita Chadda joins the lab!
Welcome to new graduate student, Ankita Chadda! Click here to learn more about her.
Our Methods paper describing single molecule studies of yeast transcription initiation is online.
Click here to see how Eric Tomko uses magnetic tweezers assays to describe mechanisms of DNA unwinding by the pre-initiation complex of S. cerevisiae.
Drake Jensen receives travel award from Biophysical Society
Eric and Drake traveled to Baltimore, MD to present their work at the 2019 Biophysical Society Meeting and eat crab cakes. Even better, Drake was chosen as a student travel awardee! A great meeting! Thank you BPS!