Our Methods paper describing single molecule studies of yeast transcription initiation is online.
Click here to see how Eric Tomko uses magnetic tweezers assays to describe mechanisms of DNA unwinding by the pre-initiation complex of S. cerevisiae.
News
Drake Jensen receives travel award from Biophysical Society
Eric and Drake traveled to Baltimore, MD to present their work at the 2019 Biophysical Society Meeting and eat crab cakes. Even better, Drake was chosen as a student travel awardee! A great meeting! Thank you BPS!
Flux calculations published in PNAS
The lab’s new resource for performing calculations of regulated transcriptional flux ratios across promoter space has been published in PNAS. Click here to see the paper.
The lab contributed to recent work on RbpA-based transcriptional regulation genome-wide published in the Journal of Bacteriology.
We contributed kinetic and thermodynamic measurements of the effects of mutant RbpA constructs on the equilibrium between open and closed complex. These mutants were used to dissect the genome-wide regulation of mycobacterial transcription in M. tuberculosis. Interestingly, RbpA mutants led… Read More »The lab contributed to recent work on RbpA-based transcriptional regulation genome-wide published in the Journal of Bacteriology.